When you watch speakers, it is always fun to look what they do with their hands as they speak. Some speakers hide their hands in their pockets. Others make a steeple or seemed to be praying. Many speakers have no clue on what to do with them and most importantly it shows. Others move their hands with no purpose as if their hands have a mind of their own. Just as your body movements on stage must have a purpose, so do hands need that same purpose.
First rule to remember is your audience always needs to see your hands move in the first place. Many speakers have a tendency to keep their hand movements down low by their sides rather than higher up near the middle of the chest where everyone can see them. Also, be and stay consistent with any sense of direction you are pointing to.